Research Assistant Professor
We innovate in vivo and in vitro cancer model systems that can be readily analyzed by genetic and molecular biology techniques. This aims to find pathways critical for carcinogenesis, metastasis, drug resistance, and stem cell-like behaviors in cancer cells. Below are ongoing projects in our laboratory.
Cellular signals merged on the modulation of pRB functions, and effectors of pRB. This at least partially explains multifaceted functions of pRB.
Stem cell-like cells appeared in cancers induced by the combinational suppression of tumor suppressor genes including Rb.